Evaluation of Whole-Genome Sequence Method to Diagnose Resistance of 13 Anti-tuberculosis Drugs and Characterize Resistance Genes in Clinical Multi-Drug Resistance Mycobacterium tuberculosis Isolates From China

Background: Whole-genome sequencing (WGS) is a viable and financially feasible tool for timely and comprehensive diagnosis of drug resistance in developed countries. With the increase in the incidence of multidrug-resistant tuberculosis (MDR-TB), second-line anti-TB drugs are gaining importance. How...

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Bibliographische Detailangaben
Veröffentlicht in:Front Microbiol
Hauptverfasser: Chen, Xinchang, He, Guiqing, Wang, Shiyong, Lin, Siran, Chen, Jiazhen, Zhang, Wenhong
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2019
Schlagworte:
Microbiology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6685394/
https://ncbi.nlm.nih.gov/pubmed/31417530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2019.01741
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