Nrf2 Induction Re-establishes a Proper Neuronal Differentiation Program in Friedreich’s Ataxia Neural Stem Cells

Frataxin deficiency is the pathogenic cause of Friedreich’s Ataxia, an autosomal recessive disease characterized by the increase of oxidative stress and production of free radicals in the cell. Although the onset of the pathology occurs in the second decade of life, cognitive differences and defects...

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Bibliographic Details
Published in:Front Cell Neurosci
Main Authors: La Rosa, Piergiorgio, Russo, Marta, D’Amico, Jessica, Petrillo, Sara, Aquilano, Katia, Lettieri-Barbato, Daniele, Turchi, Riccardo, Bertini, Enrico S., Piemonte, Fiorella
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2019
Subjects:
Neuroscience
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6685360/
https://ncbi.nlm.nih.gov/pubmed/31417369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2019.00356
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