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Unveiling the gene regulatory landscape in diseases through the identification of DNase I-hypersensitive sites

DNase I-hypersensitive sites (DHSs) serve key roles in the regulation of gene transcription as markers of cis-regulatory elements (CREs). Recent advances in next-generation sequencing have enabled the genome-wide location and annotation of DHSs in a variety of cells. Numerous studies have confirmed...

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Pubblicato in:Biomed Rep
Autori principali: Chen, Ying, Chen, Ailing
Natura: Artigo
Lingua:Inglês
Pubblicazione: D.A. Spandidos 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6684942/
https://ncbi.nlm.nih.gov/pubmed/31423302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/br.2019.1233
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