Interleukin-6/STAT3 Signaling is Prominent and Associated with Reduced Overall Survival in p16 Negative Oropharyngeal Squamous Cell Carcinoma

This study addresses the hypothesis that IL-6/STAT3 signaling is of clinical relevance in oropharyngeal squamous cell carcinoma (OPSCC). We evaluated relationships between key components of this pathway in tumors from a unique cohort of n = 59 fully annotated, treatment-naïve patients with OPSCC. Th...

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Veröffentlicht in:Head Neck Pathol
Hauptverfasser: Lesinski, Gregory B., Nannapaneni, Sreenivas, Griffith, Christopher C., Patel, Mihir, Chen, Wanqi, Chen, Zhengjia, Ahmed, Rafi, Wieland, Andreas, Shin, Dong M., Chen, Zhuo G., Saba, Nabil F.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer US 2018
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Original Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6684688/
https://ncbi.nlm.nih.gov/pubmed/30191505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12105-018-0962-y
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