Evaluation of polydentate picolinic acid chelating ligands and an α-melanocyte-stimulating hormone derivative for targeted alpha therapy using ISOL-produced (225)Ac

BACKGROUND: Actinium-225 ((225)Ac, t(1/2) = 9.9 d) is a promising candidate radionuclide for use in targeted alpha therapy (TAT), though the currently limited global supply has hindered the development of a suitable Ac-chelating ligand and (225)Ac-radiopharmaceuticals towards the clinic. We at TRIUM...

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Detalhes bibliográficos
Publicado no:EJNMMI Radiopharm Chem
Main Authors: Ramogida, Caterina F., Robertson, Andrew K. H., Jermilova, Una, Zhang, Chengcheng, Yang, Hua, Kunz, Peter, Lassen, Jens, Bratanovic, Ivica, Brown, Victoria, Southcott, Lily, Rodríguez-Rodríguez, Cristina, Radchenko, Valery, Bénard, François, Orvig, Chris, Schaffer, Paul
Formato: Artigo
Idioma:Inglês
Publicado em: Springer International Publishing 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6684685/
https://ncbi.nlm.nih.gov/pubmed/31659557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s41181-019-0072-5
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