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A Design of Experiments (DoE) Approach Accelerates the Optimization of Copper-Mediated (18)F-Fluorination Reactions of Arylstannanes
Recent advancements in (18)F radiochemistry, such as the advent of copper-mediated radiofluorination (CMRF) chemistry, have provided unprecedented access to novel chemically diverse PET probes; however, these multicomponent reactions have come with a new set of complex optimization problems. Design...
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| Publicado en: | Sci Rep |
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| Autores principales: | , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Nature Publishing Group UK
2019
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6684620/ https://ncbi.nlm.nih.gov/pubmed/31388076 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-47846-6 |
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