Rapid fabrication of vascularized and innervated cell-laden bone models with biomimetic intrafibrillar collagen mineralization

Bone tissue, by definition, is an organic–inorganic nanocomposite, where metabolically active cells are embedded within a matrix that is heavily calcified on the nanoscale. Currently, there are no strategies that replicate these definitive characteristics of bone tissue. Here we describe a biomimeti...

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Publicat a:Nat Commun
Autors principals: Thrivikraman, Greeshma, Athirasala, Avathamsa, Gordon, Ryan, Zhang, Limin, Bergan, Raymond, Keene, Douglas R., Jones, James M., Xie, Hua, Chen, Zhiqiang, Tao, Jinhui, Wingender, Brian, Gower, Laurie, Ferracane, Jack L., Bertassoni, Luiz E.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2019
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6684598/
https://ncbi.nlm.nih.gov/pubmed/31388010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-11455-8
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