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A two-step mechanism for the inactivation of microtubule organizing center function at the centrosome

The centrosome acts as a microtubule organizing center (MTOC), orchestrating microtubules into the mitotic spindle through its pericentriolar material (PCM). This activity is biphasic, cycling through assembly and disassembly during the cell cycle. Although hyperactive centrosomal MTOC activity is a...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Magescas, Jérémy, Zonka, Jenny C, Feldman, Jessica L
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6684319/
https://ncbi.nlm.nih.gov/pubmed/31246171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.47867
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