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Imiquimod and interferon-alpha augment monocyte-mediated astrocyte secretion of MCP-1, IL-6 and IP-10 in a human co-culture system

Toll-like receptor 7 (TLR7)-activation has been implicated as a significant mechanism of neuroinflammation triggered by ssRNA viruses. Infiltration of monocytes into the brain and astrocyte activation occurs during in vivo TLR7-mediated neuroinflammation. The objective here was to determine whether...

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Bibliografske podrobnosti
izdano v:J Neuroimmunol
Main Authors: RIZZO, Michael D., CRAWFORD, Robert B., BACH, Anthony, SERMET, Sera, AMALFITANO, Andrea, KAMINSKI, Norbert E.
Format: Artigo
Jezik:Inglês
Izdano: 2019
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6684287/
https://ncbi.nlm.nih.gov/pubmed/31136945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jneuroim.2019.576969
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