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Kinesin-5 promotes microtubule nucleation and assembly by stabilizing a lattice-competent conformation of tubulin
Besides sliding apart antiparallel microtubules during spindle elongation, the mitotic kinesin-5, Eg5 promotes microtubule polymerization, emphasizing its importance in mitotic spindle length control. Here, we characterize the Eg5 microtubule polymerase mechanism by assessing motor-induced changes i...
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| Publicado no: | Curr Biol |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6684259/ https://ncbi.nlm.nih.gov/pubmed/31280993 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2019.05.075 |
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