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Adolescent alcohol exposure epigenetically suppresses amygdala Arc enhancer RNA expression to confer adult anxiety susceptibility

BACKGROUND: Adolescent intermittent ethanol (AIE) exposure is an emerging risk factor for adult psychopathology such as anxiety disorders. Enhancer RNAs (eRNAs) are short non-coding RNAs transcribed from enhancer regions that regulate synaptic plasticity-associated gene expression including activity...

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Detalhes bibliográficos
Publicado no:Biol Psychiatry
Main Authors: Kyzar, Evan J., Zhang, Huaibo, Pandey, Subhash C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6684056/
https://ncbi.nlm.nih.gov/pubmed/30827484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2018.12.021
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