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Deciphering Within-Host Microevolution of Mycobacterium tuberculosis through Whole-Genome Sequencing: the Phenotypic Impact and Way Forward

The Mycobacterium tuberculosis genome is more heterogenous and less genetically stable within the host than previously thought. Currently, only limited data exist on the within-host microevolution, diversity, and genetic stability of M. tuberculosis. As a direct consequence, our ability to infer M....

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Bibliografiske detaljer
Udgivet i:Microbiol Mol Biol Rev
Main Authors: Ley, S. D., de Vos, M., Van Rie, A., Warren, R. M.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6684002/
https://ncbi.nlm.nih.gov/pubmed/30918049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MMBR.00062-18
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