Krüppel-like factor 3 inhibition by mutated lncRNA Reg1cp results in human high bone mass syndrome

High bone mass (HBM) is usually caused by gene mutations, and its mechanism remains unclear. In the present study, we identified a novel mutation in the long noncoding RNA Reg1cp that is associated with HBM. Subsequent analysis in 1,465 Chinese subjects revealed that heterozygous Reg1cp individuals...

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Dades bibliogràfiques
Publicat a:J Exp Med
Autors principals: Yang, Mi, Guo, Qi, Peng, Hui, Xiao, Yu-Zhong, Xiao, Ye, Huang, Yan, Li, Chang-Jun, Su, Tian, Zhang, Yun-Lin, Lei, Min-Xiang, Chen, Hui-Ling, Jiang, Tie-Jian, Luo, Xiang-Hang
Format: Artigo
Idioma:Inglês
Publicat: Rockefeller University Press 2019
Matèries:
Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6683986/
https://ncbi.nlm.nih.gov/pubmed/31196982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20181554
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