EMSY expression affects multiple components of the skin barrier with relevance to atopic dermatitis

BACKGROUND: Atopic dermatitis (AD) is a common, complex, and highly heritable inflammatory skin disease. Genome-wide association studies offer opportunities to identify molecular targets for drug development. A risk locus on chromosome 11q13.5 lies between 2 candidate genes, EMSY and LRRC32 (leucine...

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Vydáno v:J Allergy Clin Immunol
Hlavní autoři: Elias, Martina S., Wright, Sheila C., Remenyi, Judit, Abbott, James C., Bray, Susan E., Cole, Christian, Edwards, Sharon, Gierlinski, Marek, Glok, Mateusz, McGrath, John A., Nicholson, William V., Paternoster, Lavinia, Prescott, Alan R., Have, Sara Ten, Whitfield, Phillip D., Lamond, Angus I., Brown, Sara J.
Médium: Artigo
Jazyk:Inglês
Vydáno: Mosby 2019
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6683598/
https://ncbi.nlm.nih.gov/pubmed/31158401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2019.05.024
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