Germline and somatic mutations in patients with multiple primary melanomas: a next generation sequencing study

INTRODUCTION: Multiple primary melanomas (MPM) occur up to 8% of patients with cutaneous malignant melanoma (CMM). They are often sporadic harbouring several somatic mutations, but also familial cases harbouring a CDKN2A germline mutation have been describe in Caucasian populations. The aim of this...

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Veröffentlicht in:BMC Cancer
Hauptverfasser: Casula, Milena, Paliogiannis, Panagiotis, Ayala, Fabrizio, De Giorgi, Vincenzo, Stanganelli, Ignazio, Mandalà, Mario, Colombino, Maria, Manca, Antonella, Sini, Maria Cristina, Caracò, Corrado, Ascierto, Paolo Antonio, Satta, Rosanna Rita, Lissia, Amelia, Cossu, Antonio, Palmieri, Giuseppe
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2019
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6683413/
https://ncbi.nlm.nih.gov/pubmed/31382929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-019-5984-7
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