Clinical response to linaclotide at week 4 predicts sustained response in irritable bowel syndrome with constipation and improvements in digestive and extra-digestive symptoms

BACKGROUND: Linaclotide is approved for the treatment of moderate-to-severe irritable bowel syndrome (IBS) with constipation (IBS-C) in adults. This study aimed to assess factors predictive of a clinical response and improvements in non-IBS symptoms with linaclotide treatment in a Spanish patient po...

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Detalhes bibliográficos
Publicado no:Therap Adv Gastroenterol
Main Authors: Serrano-Falcón, Blanca, Delgado-Aros, Sílvia, Mearin, Fermín, Ciriza de los Ríos, Constanza, Serra, Jordi, Mínguez, Miguel, Montoro Huguet, Miguel, Perelló, Antonia, Santander, Cecilio, Pérez Aisa, Ángeles, Bañón-Rodríguez, Inmaculada, Rey, Enrique
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2019
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Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6683318/
https://ncbi.nlm.nih.gov/pubmed/31428193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1756284819857358
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