Cyclooxygenase inhibitors impair CD4 T cell immunity and exacerbate Mycobacterium tuberculosis infection in aerosol-challenged mice

Tuberculosis, caused by infection with Mycobacterium tuberculosis (Mtb), kills over 1.6 million people each year despite availability of antibiotics. The increase in drug resistant Mtb strains is a major public health emergency and host-directed therapy as adjunct to antibiotic treatment has gained...

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Detalhes bibliográficos
Publicado no:Commun Biol
Main Authors: Mortensen, Rasmus, Clemmensen, Helena Strand, Woodworth, Joshua S., Therkelsen, Marie Louise, Mustafa, Tehmina, Tonby, Kristian, Jenum, Synne, Agger, Else Marie, Dyrhol-Riise, Anne Ma, Andersen, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6683187/
https://ncbi.nlm.nih.gov/pubmed/31396568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-019-0530-3
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