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Structure functional insights into calcium binding during the activation of coagulation factor XIII A
The dimeric FXIII-A(2), a pro-transglutaminase is the catalytic part of the heterotetrameric coagulation FXIII-A(2)B(2) complex that upon activation by calcium binding/thrombin cleavage covalently cross-links preformed fibrin clots protecting them from premature fibrinolysis. Our study characterizes...
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| Udgivet i: | Sci Rep |
|---|---|
| Main Authors: | , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group UK
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6683118/ https://ncbi.nlm.nih.gov/pubmed/31383913 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-47815-z |
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