Co-loading antioxidant N-acetylcysteine attenuates cytotoxicity of iron oxide nanoparticles in hypoxia/reoxygenation cardiomyocytes

PURPOSE: Myocardial delivery of magnetic iron oxide nanoparticles (MNPs) might produce iron overload-induced myocardial injury, and the oxidative stress was regarded as the main mechanism. Therefore, we speculated antioxidant modification might be a reasonable strategy to mitigate the toxicity of MN...

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Detalhes bibliográficos
Publicado no:Int J Nanomedicine
Main Authors: Shen, Yunli, Gong, Shiyu, Li, Jiming, Wang, Yunkai, Zhang, Xumin, Zheng, Hao, Zhang, Qi, You, Jieyun, Huang, Zheyong, Chen, Yihan
Formato: Artigo
Idioma:Inglês
Publicado em: Dove 2019
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6682760/
https://ncbi.nlm.nih.gov/pubmed/31447555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S209820
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