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LIM-domain transcription complexes interact with ring-finger ubiquitin ligases and thereby impact islet β-cell function

Diabetes is characterized by a loss of β-cell mass, and a greater understanding of the transcriptional mechanisms governing β-cell function is required for future therapies. Previously, we reported that a complex of the Islet-1 (Isl1) transcription factor and the co-regulator single-stranded DNA–bin...

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Dettagli Bibliografici
Pubblicato in:J Biol Chem
Autori principali: Wade, Alexa K., Liu, Yanping, Bethea, Maigen M., Toren, Eliana, Tse, Hubert M., Hunter, Chad S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6682733/
https://ncbi.nlm.nih.gov/pubmed/31186351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.006985
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