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Bottom-up and top-down profiling of pentosan polysulfate

Pentosan polysulfate (PPS) is a semi-synthetic glycosaminoglycan (GAG) mimetic. PPS, synthesized through the chemical sulfonation of a plant-derived β-(1→4)-xylan, is the active pharmaceutical ingredient of the drug Elmiron™ used to treat interstitial cystitis. Unlike natural GAGs that can be enzyma...

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書目詳細資料
發表在:Analyst
Main Authors: Lin, Lei, Yu, Yanlei, Zhang, Fuming, Xia, Ke, Zhang, Xing, Linhardt, Robert J
格式: Artigo
語言:Inglês
出版: 2019
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6682433/
https://ncbi.nlm.nih.gov/pubmed/31287456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c9an01006h
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