Optimization-by-design of hepatotropic lipid nanoparticles targeting the sodium-taurocholate cotransporting polypeptide

Active targeting and specific drug delivery to parenchymal liver cells is a promising strategy to treat various liver disorders. Here, we modified synthetic lipid-based nanoparticles with targeting peptides derived from the hepatitis B virus large envelope protein (HBVpreS) to specifically target th...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:eLife
Hlavní autoři: Witzigmann, Dominik, Uhl, Philipp, Sieber, Sandro, Kaufman, Christina, Einfalt, Tomaz, Schöneweis, Katrin, Grossen, Philip, Buck, Jonas, Ni, Yi, Schenk, Susanne H, Hussner, Janine, Meyer zu Schwabedissen, Henriette E, Québatte, Gabriela, Mier, Walter, Urban, Stephan, Huwyler, Jörg
Médium: Artigo
Jazyk:Inglês
Vydáno: eLife Sciences Publications, Ltd 2019
Témata:
Biochemistry and Chemical Biology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6682401/
https://ncbi.nlm.nih.gov/pubmed/31333191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.42276
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky