Characterization of the tumor immune micromilieu and its interference with outcome after concurrent chemoradiation in patients with oropharyngeal carcinomas

Background: Intra-tumoral CD8 + T-cell infiltration in squamous cell carcinoma of the head and neck (HNSCC) has previously been linked to the efficacy of cisplatin-based chemoradiation (CDDP-CRTX) and immune checkpoint inhibitor (ICI) monotherapy. Further detailed characterization of the tumor immun...

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Vydáno v:Oncoimmunology
Hlavní autoři: Hess, Anne-Kathrin, Jöhrens, Korinna, Zakarneh, Andre, Balermpas, Panagiotis, Von Der Grün, Jens, Rödel, Claus, Weichert, Wilko, Hummel, Michael, Keilholz, Ulrich, Budach, Volker, Tinhofer, Ingeborg
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis 2019
Témata:
Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6682352/
https://ncbi.nlm.nih.gov/pubmed/31413922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2019.1614858
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