Prognostic significance of human telomerase reverse transcriptase promoter region mutations C228T and C250T for overall survival in spinal chordomas

BACKGROUND: Spinal chordomas, a subtype of primary spinal column malignancies (PSCM), are rare tumors with poor prognosis, and we have limited understanding of the molecular drivers of neoplasia. METHODS: Study design was a retrospective review of prospectively collected data with cross-sectional su...

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發表在:Neuro Oncol
Main Authors: Bettegowda, Chetan, Yip, Stephen, Jiang, Bowen, Wang, Wei-Lien, Clarke, Michelle J, Lazary, Aron, Gambarotti, Marco, Zhang, Ming, Sciubba, Daniel M, Wolinsky, Jean-Paul, Goodwin, C Rory, McCarthy, Edward, Germscheid, Niccole M, Sahgal, Arjun, Gokaslan, Ziya L, Boriani, Stefano, Varga, Peter Pal, Fisher, Charles G, Rhines, Laurence D
格式: Artigo
語言:Inglês
出版: Oxford University Press 2019
主題:
Basic and Translational Investigations
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6682209/
https://ncbi.nlm.nih.gov/pubmed/30976795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz066
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