TAp73 expression and P1 promoter methylation, a potential marker for chemoresponsiveness to cisplatin therapy and survival in muscle-invasive bladder cancer (MIBC)

Intrinsic and/or acquired resistance to cisplatin is a significant obstacle in the treatment of muscle-invasive bladder cancer. p73, a p53 homolog and determinant of chemosensitivity, is rarely mutated in bladder cancer (BC). However p73 expression and therefore function can be repressed through epi...

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Vydáno v:Cell Cycle
Hlavní autoři: Bunch, Brittany, Krishnan, Nithya, Greenspan, Rebecca D., Ramakrishnan, Swathi, Attwood, Kristopher, Yan, Li, Qi, Qianya, Wang, Dan, Morrison, Carl, Omilian, Angela, Bshara, Wiam, Pili, Roberto, Trump, Donald L., Johnson, Candace, Woloszynska, Anna
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis 2019
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6681839/
https://ncbi.nlm.nih.gov/pubmed/31318640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2019.1638693
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