BCL-2 family protein BOK is a positive regulator of uridine metabolism in mammals

BCL-2 family proteins regulate the mitochondrial apoptotic pathway. BOK, a multidomain BCL-2 family protein, is generally believed to be an adaptor protein similar to BAK and BAX, regulating the mitochondrial permeability transition during apoptosis. Here we report that BOK is a positive regulator o...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Srivastava, Rahul, Cao, Zhipeng, Nedeva, Christina, Naim, Samara, Bachmann, Daniel, Rabachini, Tatiana, Gangoda, Lahiru, Shahi, Sanjay, Glab, Jason, Menassa, Joseph, Osellame, Laura, Nelson, Tao, Fernandez-Marrero, Yuniel, Brown, Fiona, Wei, Andrew, Ke, Francine, O’Reilly, Lorraine, Doerflinger, Marcel, Allison, Cody, Kueh, Andrew, Ramsay, Rob, Smith, Brian J., Mathivanan, Suresh, Kaufmann, Thomas, Puthalakath, Hamsa
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2019
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6681708/
https://ncbi.nlm.nih.gov/pubmed/31311867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1904523116
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