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The Developmental Neurotoxicity of Tobacco Smoke Can Be Mimicked by a Combination of Nicotine and Benzo[a]Pyrene: Effects on Cholinergic and Serotonergic Systems

Tobacco smoke contains polycyclic aromatic hydrocarbons (PAHs) in addition to nicotine. We compared the developmental neurotoxicity of nicotine to that of the PAH archetype, benzo[a]pyrene (BaP), and also evaluated the effects of combined exposure to assess whether PAHs might exacerbate the adverse...

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Detalhes bibliográficos
Publicado no:Toxicol Sci
Main Authors: Slotkin, Theodore A, Skavicus, Samantha, Ko, Ashley, Levin, Edward D, Seidler, Frederic J
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6681680/
https://ncbi.nlm.nih.gov/pubmed/30247698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfy241
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