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Longitudinal Morphological and Physiological Monitoring of Three-dimensional Tumor Spheroids Using Optical Coherence Tomography

Tumor spheroids have been developed as a three-dimensional (3D) cell culture model in cancer research and anti-cancer drug discovery. However, currently, high-throughput imaging modalities utilizing bright field or fluorescence detection, are unable to resolve the overall 3D structure of the tumor s...

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Bibliographische Detailangaben
Veröffentlicht in:J Vis Exp
Hauptverfasser: Huang, Yongyang, Zou, Jinyun, Badar, Mudabbir, Liu, Junchao, Shi, Wentao, Wang, Shunqiang, Guo, Qiongyu, Wang, Xiaofang, Kessel, Sarah, Chan, Leo Li-Ying, Li, Peter, Liu, Yaling, Qiu, Jean, Zhou, Chao
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6681648/
https://ncbi.nlm.nih.gov/pubmed/30799861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/59020
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