Therapeutic Silencing of Centromere Protein X Ameliorates Hyperglycemia in Zebrafish and Mouse Models of Type 2 Diabetes Mellitus

Type 2 diabetes mellitus (T2DM) is characterized by persistent hyperglycemia and is influenced by genetic and environmental factors. Optimum T2DM management involves early diagnosis and effective glucose-lowering therapies. Further research is warranted to improve our understanding of T2DM pathophys...

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Bibliographic Details
Published in:Front Genet
Main Authors: Zang, Liqing, Shimada, Yasuhito, Nakayama, Hiroko, Chen, Wenbiao, Okamoto, Ayaka, Koide, Hiroyuki, Oku, Naoto, Dewa, Takehisa, Shiota, Masayuki, Nishimura, Norihiro
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2019
Subjects:
Genetics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6681619/
https://ncbi.nlm.nih.gov/pubmed/31417608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2019.00693
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