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Association of Asymmetric Dimethylarginine and Diastolic Dysfunction in Patients with Hypertrophic Cardiomyopathy

Despite genetic heterogeneity, early manifestation of diastolic dysfunction (DD) is common in hypertrophic cardiomyopathy (HCM). Nitric oxide (NO) may contribute to myocardial relaxation. NO synthases (NOS) use l-arginine (Arg) as a substrate, as asymmetric dimethylarginine (ADMA) is a direct endoge...

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Detalhes bibliográficos
Publicado no:Biomolecules
Main Authors: Cordts, Kathrin, Seelig, Doreen, Lund, Natalie, Carrier, Lucie, Böger, Rainer H., Avanesov, Maxim, Tahir, Enver, Schwedhelm, Edzard, Patten, Monica
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6681289/
https://ncbi.nlm.nih.gov/pubmed/31337005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom9070277
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