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A Sesquiterpenoid from Farfarae Flos Induces Apoptosis of MDA-MB-231 Human Breast Cancer Cells through Inhibition of JAK–STAT3 Signaling

Triple-negative breast cancers (TNBCs) are hard-to-treat breast tumors with poor prognosis, which need to be treated by chemotherapy. Signal transducer and activator of transcription 3 (STAT3) is a transcription factor involved in proliferation, metastasis, and invasion of cancer cells. Therefore, r...

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Detalhes bibliográficos
Publicado no:Biomolecules
Main Authors: Jang, Hyeri, Ko, Hyejin, Song, Kwangho, Kim, Yeong Shik
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6681226/
https://ncbi.nlm.nih.gov/pubmed/31337063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom9070278
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