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Withanolides, Extracted from Datura Metel L. Inhibit Keratinocyte Proliferation and Imiquimod-Induced Psoriasis-Like Dermatitis via the STAT3/P38/ERK1/2 Pathway

Psoriasis is an immune-mediated inflammatory dermatosis characterized by epidermal hyperplasia and excessive infiltration of inflammatory cells. Withanolides, extracted from Datura metel L.; are the main effective components for the treatment of psoriasis. However, the precise mechanisms of action o...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Li, Tingting, Wei, Zheng, Sun, Yanping, Wang, Qiuhong, Kuang, Haixue
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6680890/
https://ncbi.nlm.nih.gov/pubmed/31319488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules24142596
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