Self‐Assembly of Measles Virus Nucleocapsid‐like Particles: Kinetics and RNA Sequence Dependence

Measles virus RNA genomes are packaged into helical nucleocapsids (NCs), comprising thousands of nucleo‐proteins (N) that bind the entire genome. N‐RNA provides the template for replication and transcription by the viral polymerase and is a promising target for viral inhibition. Elucidation of mecha...

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Detalhes bibliográficos
Publicado no:Angew Chem Int Ed Engl
Main Authors: Milles, Sigrid, Jensen, Malene Ringkjøbing, Communie, Guillaume, Maurin, Damien, Schoehn, Guy, Ruigrok, Rob W. H., Blackledge, Martin
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Communications
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6680290/
https://ncbi.nlm.nih.gov/pubmed/27270664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201602619
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