Thymidylate synthase expression in circulating tumor cells: A new tool to predict 5‐fluorouracil resistance in metastatic colorectal cancer patients

Thymidylate synthase (TYMS) is an important enzyme for 5‐fluorouracil (5‐FU) metabolism in metastatic colorectal cancer (mCRC) patients. The search for this enzyme in circulating tumor cells (CTCs) can be a powerful tool to follow‐up cancer patients. mCRC patients were enrolled before the beginning...

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Dettagli Bibliografici
Pubblicato in:Int J Cancer
Autori principali: Abdallah, Emne Ali, Fanelli, Marcello Ferretti, Buim, Marcilei Eliza Cavicchioli, Machado Netto, Marcelo Calil, Gasparini Junior, José Luiz, Souza e Silva, Virgílio, Dettino, Aldo Lourenço Abbade, Mingues, Natalia Breve, Romero, Juliana Valim, Ocea, Luciana Menezes Mendonça, Rocha, Bruna Maria Malagoli, Alves, Vanessa Silva, Araújo, Daniel Vilarim, Chinen, Ludmilla Thomé Domingos
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2015
Soggetti:
Early Detection and Diagnosis
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6680263/
https://ncbi.nlm.nih.gov/pubmed/25721610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.29495
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