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EP3 receptor antagonist L798,106 reduces proliferation and migration of SK-BR-3 breast cancer cells

Purpose: COX-2 overexpression and elevated levels of prostaglandin E2 (PGE2) play an important role in breast cancer carcinogenesis. Recently, expression of the PGE2 receptor EP3 has been shown to be a positive prognostic factor in breast cancer. This study analyzes the functional aspects of targeti...

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Dettagli Bibliografici
Pubblicato in:Onco Targets Ther
Autori principali: Hester, Anna, Salzmann, Barbara, Rahmeh, Martina, Kolben, Thomas, Czogalla, Bastian, Ditsch, Nina, Mahner, Sven, Jeschke, Udo, Kolben, Theresa Maria
Natura: Artigo
Lingua:Inglês
Pubblicazione: Dove 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6680222/
https://ncbi.nlm.nih.gov/pubmed/31534346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S204919
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