Zinc-Induced SUMOylation of Dynamin-Related Protein 1 Protects the Heart against Ischemia-Reperfusion Injury

BACKGROUND: Zinc plays a role in mitophagy and protects cardiomyocytes from ischemia/reperfusion injury. This study is aimed at investigating whether SUMOylation of Drp1 is involved in the protection of zinc ion on cardiac I/R injury. METHODS: Mouse hearts were subjected to 30 minutes of regional is...

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Pubblicato in:Oxid Med Cell Longev
Autori principali: Bian, Xiyun, Xu, Jingman, Zhao, Huanhuan, Zheng, Quan, Xiao, Xiaolin, Ma, Xiaofang, Li, Yanxia, Du, Xinping, Liu, Xiaozhi
Natura: Artigo
Lingua:Inglês
Pubblicazione: Hindawi 2019
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6679852/
https://ncbi.nlm.nih.gov/pubmed/31428220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/1232146
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