Llwytho...

Genome-Wide Linkage Analysis and Whole-Exome Sequencing Identifies an ITGA2B Mutation in a Family with Thrombocytopenia

Hereditary thrombocytopenias can be subclassified based on mode of inheritance and platelet size. Here we report a family with autosomal dominant (AD) thrombocytopenia with normal platelet size. Linkage analysis and whole exome sequencing identified the R1026W substitution in ITGA2B as the causative...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Br J Haematol
Prif Awduron: Khoriaty, Rami, Ozel, Ayse Bilge, Ramdas, Shweta, Ross, Charles, Desch, Karl, Shavit, Jordan A., Everett, Lesley, Siemieniak, David, Li, Jun Z., Ginsburg, David
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2019
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6679728/
https://ncbi.nlm.nih.gov/pubmed/31119735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bjh.15961
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!