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Integrating tacrolimus into eutectic oil-based microemulsion for atopic dermatitis: simultaneously enhancing percutaneous delivery and treatment efficacy with relieving side effects

Background: Topical application of tacrolimus (FK506) was effective in treating atopic dermatitis (AD); however, the therapeutic efficiency is hampered by its poor penetration into the skin and local side effects of transient irritation symptoms with a burning sensation, a feeling of warmth or heat....

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Int J Nanomedicine
Hauptverfasser: Wang, Yixuan, Cao, Sisi, Yu, Kaiyue, Yang, Fengdie, Yu, Xiuming, Zhai, Yuanhao, Wu, Chuanbin, Xu, Yuehong
Format: Artigo
Sprache:Inglês
Veröffentlicht: Dove 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6679700/
https://ncbi.nlm.nih.gov/pubmed/31440050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S212260
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