Active receptor tyrosine kinases, but not Brachyury, are sufficient to trigger chordoma in zebrafish

The aberrant activation of developmental processes triggers diverse cancer types. Chordoma is a rare, aggressive tumor arising from transformed notochord remnants. Several potentially oncogenic factors have been found to be deregulated in chordoma, yet causation remains uncertain. In particular, sus...

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Bibliografiske detaljer
Udgivet i:Dis Model Mech
Main Authors: D'Agati, Gianluca, Cabello, Elena María, Frontzek, Karl, Rushing, Elisabeth J., Klemm, Robin, Robinson, Mark D., White, Richard M., Mosimann, Christian, Burger, Alexa
Format: Artigo
Sprog:Inglês
Udgivet: The Company of Biologists Ltd 2019
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6679381/
https://ncbi.nlm.nih.gov/pubmed/31221659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.039545
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