Development of mouse models of angiosarcoma driven by p53

Angiosarcomas are a rare group of tumours which have poor prognosis and limited treatment options. The development of new therapies has been hampered by a lack of good preclinical models. Here, we describe the development of an autochthonous mouse model of angiosarcoma driven by loss of p53 in VE-ca...

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Detalhes bibliográficos
Publicado no:Dis Model Mech
Main Authors: Salter, Donald M., Griffin, Meredyth, Muir, Morwenna, Teo, Katy, Culley, Jayne, Smith, James R., Gomez-Cuadrado, Laura, Matchett, Kylie, Sims, Andrew H., Hayward, Larry, Henderson, Neil C., Brunton, Valerie G.
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6679377/
https://ncbi.nlm.nih.gov/pubmed/31221668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.038612
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