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Defining Bronchial Asthma with Phosphoinositide 3-Kinase Delta Activation: Towards Endotype-Driven Management

Phosphoinositide 3-kinase (PI3K) pathways play a critical role in orchestrating the chronic inflammation and the structural changes of the airways in patients with asthma. Recently, a great deal of progress has been made in developing selective and effective PI3K-targeted therapies on the basis of a...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Jeong, Jae Seok, Kim, Jong Seung, Kim, So Ri, Lee, Yong Chul
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6679152/
https://ncbi.nlm.nih.gov/pubmed/31323822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20143525
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