Deciphering the Molecular Basis of Melatonin Protective Effects on Breast Cells Treated with Doxorubicin: TWIST1 a Transcription Factor Involved in EMT and Metastasis, a Novel Target of Melatonin

Melatonin mitigates cancer initiation, progression and metastasis through inhibition of both the synthesis of estrogens and the transcriptional activity of the estradiol-ER (Estrogen receptor) complex in the estrogen-dependent breast cancer cell line MCF-7. Moreover, melatonin improves the sensitivi...

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Detalles Bibliográficos
Publicado en:Cancers (Basel)
Main Authors: Menéndez-Menéndez, Javier, Hermida-Prado, Francisco, Granda-Díaz, Rocío, González, Alicia, García-Pedrero, Juana María, Del-Río-Ibisate, Nagore, González-González, Alicia, Cos, Samuel, Alonso-González, Carolina, Martínez-Campa, Carlos
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2019
Assuntos:
Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6679136/
https://ncbi.nlm.nih.gov/pubmed/31331001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers11071011
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