Combined Treatment with MEK and mTOR Inhibitors is Effective in In Vitro and In Vivo Models of Hepatocellular Carcinoma

Background: Hepatocellular carcinoma (HCC) is the most common primary liver cancer histotype, characterized by high biological aggressiveness and scarce treatment options. Recently, we have established a clinically relevant murine HCC model by co-expressing activated forms of v-akt murine thymoma vi...

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Опубликовано в: :Cancers (Basel)
Главные авторы: Liu, Xianqiong, Hu, Junjie, Song, Xinhua, Utpatel, Kirsten, Zhang, Yi, Wang, Pan, Lu, Xinjun, Zhang, Jie, Xu, Meng, Su, Tao, Che, Li, Wang, Jingxiao, Evert, Matthias, Calvisi, Diego F., Chen, Xin
Формат: Artigo
Язык:Inglês
Опубликовано: MDPI 2019
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6679026/
https://ncbi.nlm.nih.gov/pubmed/31277283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers11070930
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