Dietary Cholesterol Is Highly Associated with Severity of Hyperlipidemia and Atherosclerotic Lesions in Heterozygous LDLR-Deficient Hamsters

Objective: Familial hypercholesterolemia (FH) is a dominant inherited disease caused mainly by low-density lipoprotein receptor (LDLR) gene mutations. To different extents, both heterozygous and homozygous FH patients develop premature coronary heart disease (CHD). However, most of the experimental...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Wang, Jinjie, He, Kunxiang, Yang, Chun, Lin, Xiao, Zhang, Xin, Wang, Yuhui, Liu, George, Xian, Xunde
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6678973/
https://ncbi.nlm.nih.gov/pubmed/31323736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20143515
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