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Reactions in the Radiosensitizer Misonidazole Induced by Low-Energy (0–10 eV) Electrons

Misonidazole (MISO) was considered as radiosensitizer for the treatment of hypoxic tumors. A prerequisite for entering a hypoxic cell is reduction of the drug, which may occur in the early physical-chemical stage of radiation damage. Here we study electron attachment to MISO and find that it very ef...

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Publicat a:Int J Mol Sci
Autors principals: Meißner, Rebecca, Feketeová, Linda, Illenberger, Eugen, Denifl, Stephan
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2019
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6678818/
https://ncbi.nlm.nih.gov/pubmed/31315268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20143496
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