Somatic Alteration Burden Involving Non-Cancer Genes Predicts Prognosis in Early-Stage Non-Small Cell Lung Cancer

The burden of somatic mutations and neoantigens has been associated with improved survival in cancer treated with immunotherapies, especially non-small cell lung cancer (NSCLC). However, there is uncertainty about their effect on outcome in early-stage untreated cases. We posited that the burden of...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Wang, Dennis, Pham, Nhu-An, Freeman, Timothy M., Raghavan, Vibha, Navab, Roya, Chang, Jonathan, Zhu, Chang-Qi, Ly, Dalam, Tong, Jiefei, Wouters, Bradly G., Pintilie, Melania, Moran, Michael F., Liu, Geoffrey, Shepherd, Frances A., Tsao, Ming-Sound
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6678704/
https://ncbi.nlm.nih.gov/pubmed/31330989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers11071009
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