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Arachidonic Acid Evokes an Increase in Intracellular Ca(2+) Concentration and Nitric Oxide Production in Endothelial Cells from Human Brain Microcirculation

It has long been known that the conditionally essential polyunsaturated arachidonic acid (AA) regulates cerebral blood flow (CBF) through its metabolites prostaglandin E2 and epoxyeicosatrienoic acid, which act on vascular smooth muscle cells and pericytes to vasorelax cerebral microvessels. However...

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Detalhes bibliográficos
Publicado no:Cells
Main Authors: Berra-Romani, Roberto, Faris, Pawan, Negri, Sharon, Botta, Laura, Genova, Tullio, Moccia, Francesco
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6678502/
https://ncbi.nlm.nih.gov/pubmed/31323976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells8070689
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