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Reduced Expression of Sprouty1 Contributes to the Aberrant Proliferation and Impaired Apoptosis of Acute Myeloid Leukemia Cells

In most of the acute myeloid leukemia patients there is an aberrant tyrosine kinase activity. The prototype of Sprouty proteins was originally identified in Drosophila melanogaster as antagonists of Breathless, the mammalian ortholog of fibroblast growth factor receptor. Usually, SPRY family members...

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Библиографические подробности
Опубликовано в: :J Clin Med
Главные авторы: Rosso, Valentina, Panuzzo, Cristina, Petiti, Jessica, Carturan, Sonia, Dragani, Matteo, Andreani, Giacomo, Fava, Carmen, Saglio, Giuseppe, Bracco, Enrico, Cilloni, Daniela
Формат: Artigo
Язык:Inglês
Опубликовано: MDPI 2019
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6678378/
https://ncbi.nlm.nih.gov/pubmed/31277439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/jcm8070972
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