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Loss of Wwox Causes Defective Development of Cerebral Cortex with Hypomyelination in a Rat Model of Lethal Dwarfism with Epilepsy

WW domain-containing oxidoreductase (Wwox) is a putative tumor suppressor. Several germline mutations of Wwox have been associated with infant neurological disorders characterized by epilepsy, growth retardation, and early death. Less is known, however, about the pathological link between Wwox mutat...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Int J Mol Sci
Main Authors: Tochigi, Yuki, Takamatsu, Yutaka, Nakane, Jun, Nakai, Rika, Katayama, Kentaro, Suzuki, Hiroetsu
פורמט: Artigo
שפה:Inglês
יצא לאור: MDPI 2019
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC6678113/
https://ncbi.nlm.nih.gov/pubmed/31340538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20143596
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