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Design of novel JAK3 Inhibitors towards Rheumatoid Arthritis using molecular docking analysis

Multiple cytokines play a pivotal role in the pathogenesis of Rheumatoid Arthritis by inducing intracellular signaling and it is known that the members of the Janus kinase (JAK) family are essential for such signal transduction. Janus kinase 3 is a tyrosine kinase that belongs to the Janus family of...

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Vydáno v:Bioinformation
Hlavní autoři: Jain, Divya, Udhwani, Trishang, Sharma, Shreshtha, Gandhe, Aishwarya, Reddy, Palugulla Bhaskar, Nayarisseri, Anuraj, Singh, Sanjeev Kumar
Médium: Artigo
Jazyk:Inglês
Vydáno: Biomedical Informatics 2019
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6677909/
https://ncbi.nlm.nih.gov/pubmed/31435152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.6026/97320630015068
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